Description of Urea and Creatinine Levels in Patients with Chronic Kidney Disease at Anutaputa General Hospital, Palu, 2024

Abstract

ABSTRACT

Chronic Kidney Disease (CKD) is defined as the presence of abnormalities either structurally or functionally of the kidneys, which occurs for at least three months, which has an impact on health. The prevalence rate of chronic kidney disease diagnosed by doctors in the population ≥ 15 years in Indonesia in 2018 reached 0.38% of the Indonesian population. One way to establish a diagnosis of CKD is by assessing or measuring serum urea and creatinine levels, because both compounds can be used to assess kidney function. The description of urea and creatinine in chronic kidney disease patients at Anutapura Regional Hospital, Palu in 2024 is known. This study was descriptive study with a cross-sectional approach with secondary data as a reference. The sampling technique used total sampling. Each data is described by univariate analysis using the SPSS program. The distribution of chronic kidney disease sufferers obtained that female gender is the most sufferers, namely 37 people (60.7%), and male as many as 24 people (39.3%). The highest age is 56-65 years as many as 19 people (31.1%), followed by 36-45 years and 46-55 years as many as 15 people (24.6%), then 26-35 years as many as 7 people (11.5%), and the lowest age> 65 years as many as 5 people (8.2%). The most comorbid is hypertension as many as 32 people (52.5%), followed by without hypertension and diabetes mellitus as many as 16 people (26.2%), then with hypertension and diabetes mellitus as many as 9 people (14.8%) and the lowest diabetes mellitus as many as 4 people (6.6%). The distribution of urea levels obtained the highest average urea levels in males, namely 186.54 mg / dL while women were 152.51 mg / dL. The age with the highest average urea level is 36-45 years old, which is 178.73 mg/dL, followed by 56-65 years old, which is 169.84 mg/dL, and 46-55 years old, which is 163.07 mg/dL, then 26-35 years old, which is 160.00 mg/dL, and the lowest is in those aged > 65 years, which is 129.20 mg/dL. Comorbidities with the highest average urea level are diabetes mellitus, which is 221.50 mg/dL, followed by without hypertension and diabetes mellitus, which is 168.56 mg/dL, then hypertension, which is 160.91 mg/dL, and the lowest in those with hypertension and diabetes mellitus, which is 154.22 mg/dL. The distribution of creatinine levels obtained the highest average creatinine levels in males, which is 12.60 mg/dL, while in females it is 9.06 mg/dL. The age with the highest average creatinine levels is 36-45 years of age, which is 14.48 mg/dL, followed by 26-35 years of age, which is 11.23 mg/dL, and 46-55 years of age, which is 10.34 mg/dL, then 56-65 years of age, which is 8.50 mg/dL, and the lowest in > 65 years of age, which is 5.06mg/dL. The comorbidity with the highest average creatinine level was hypertension, which was 11.10 mg/dL, followed by those with hypertension and diabetes mellitus, which was 10.84 mg/dL, then diabetes mellitus, which was 10.29 mg/dL, and the lowest was without hypertension and diabetes mellitus, which was 8.98 mg/dL. The most cases of chronic kidney disease were found in women, aged 56-65 years and comorbid hypertension. The highest average urea levels were found in men, aged 36-45 years and comorbid diabetes mellitus. The highest average urea levels were found in men, aged 36-45 years and comorbid hypertension.